Introduction

Squid provides a full suite of hardware and software components for rapidly configuring high-performance microscopes tailored to users' applications with reduced cost, effort and turnaround time. Besides increasing accessibility of research microscopes and available microscope hours to labs, it is also designed to simplify development and dissemination of new or otherwise advanced microscopy techniques.

Applications include

• slide scanner for digital pathology (including at point of care and in low-resource settings)
• time lapse imaging with 2D or 3D tiling
• spatial omics that involves multicolor and multi-round imaging
• tracking microscopy
• computational microscopy, including label free microscopy using phase/polarization/reflectance + deep learning
• super resolution microscopy
• light sheet microscopy

Assets

• main software repo: GitHub
• tracking software repo: GitHub
• CAD models/photos of assembled squids: Google Drive (newer versions now to be documented)
• BOM for the microscope, including CAD files for CNC machining: link
• (new 06/2021) BOM for 130 mm x 130 mm stage for well plate: link
• BOM for the multicolor laser engine: link
• BOM and fabrication files for the control panel: link